Pharmaceutical Products
Description
Nandrolone is an anabolic steroid. Nandrolone is most commonly sold commercially as its decanoateester and less commonly as a phenylpropionate ester (Durabolin). Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women (though now not recommended) at a dose of 50 mg every three weeks. It is also used for some aplastic anemias.
The positive effects of the drug include muscle growth, appetite stimulation and increased red blood cell production and bone density. Clinical studies have shown it to be effective in treating anaemia, osteoporosis and some forms of neoplasiaincluding breast cancer, and also acts as a progestin-based contraceptive. For these reasons,[citation needed] in the United States nandrolone received FDA approval in 1983.
Because nandrolone is not broken down into DHT, the deleterious effects common to most anabolic steroids on the scalp, skin, and prostate are lessened to a degree; but is rather broken down to the much weaker androgen dihydronandrolone. The lack of alkylation on the 17α-carbon drastically reduces the drug& acute;s liver toxicity. Estrogenic effects resulting from reaction witharomatase are also reduced due to lessened enzyme interaction,[1] but effects such as gynaecomastia and reduced libido still occur in larger doses because of other mechanisms. Other side-effects of abuse can include erectile dysfunction andcardiovascular damage, as well as several ailments resulting from the drug& acute;s effect of lowering levels of luteinizing hormonethrough negative feedback. Erectile dysfunction is attributed to the weaker action of dihydronandrolone in the penis since dihydrotestosterone is a known sexual modulator.
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Zhuhai Yuansen Bio-Tech Co., Ltd.
pharmaceutical intermediates
Address: Room 508, Huaxing Building110, Yuanlin Road, Jida, Zhuhai, Guangdong, China,
zhuhai, guangdong
China, 519000
Tel: 86-18928065602
Fax: 86-756-8800253
