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u47700,47700, u47700 powder,china u47700 supplier

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Description

Basic Information:

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Product name | U-47700 |
CAS | 82657-23-6 |
IUPAC name | 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide |
Formula | C16H22Cl2N2O |
Molecular weight | 329.27g/mol |
Compound purity | 99.5% |
Appearance | white powder |
Application | For lab research |
Storage | Keep in cool and dry place |
Package | aluminium alloy bag or according to requirement |
Place of origin | Shanghai |
Type of shipping | EMS, TNT, FEDEX, DHL, UPS |
Payment terms | T/T or Western Union or Money Gram or Bitcoin |
Delivery time | Within 1-3 days |
MOQ | 10g |
Production capacity | 500kg/month |
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Product Description:

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U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the μ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphinein animal models.

U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.

U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures.Although not used medically, the selective kappa ligands are used in research.

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Name | Replacement |
Ethylone | Dibutylone |
Ethylone | BK-EDBP |
a-pvp | 4C-PVP |
a-pvp | TH-PVP |
a-pvp | 4f-php |
4-cmc | 2-NMC |
4-cmc | 4-CEC |
3-cmc | 4-CPRC |
EP | Dimethylphenidate(DP) |
ab-chminaca | mab-chminaca (MABC) |
JWH/5F-PB22/FUB-PB22 | 5F-PCN |
AH-7921 | U-47700 |
PB-22/ AM2201 | FDU-PB-22 |
AB-FUBINACA | ADB-FUBINACA |
SDB-006 | 5F-sdb005 |
AKB-48 | FUB-AKB48 |
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Dibutylone | BK-EBDP |
4-MPD | Fub-amb |
2NMC | 4-CEC |
4BMC | BB-22 |
5F-AEB | Eg2201 |
MPHP | 4cprc |
Mmb-chminaca | mab-chminaca |
4-EMC | TH-PVP |
FUB-AMB | 4clpvp |
5F-PCN | Etizolam |
4C-PVP | 4F-PHP |
U-47700 | FDU-PB-22 |
ADB-FUBINACA | 5F-sdb005 |
NM-2201 | FUB-AKB48 |
PV10 powder | ? |
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