Chemical Machinery
CAS 50-02-2 Anti - Inflammation Glucocorticoid Steroids DMT Hormone Dexamethasone
50-02-2
Description
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CAS 50-02-2 Anti - Inflammation Glucocorticoid Steroids DMT Hormone Dexamethasone
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Product Name: Dexamethasone CAS: 50-02-2
Synonyms: 16alpha)-;6alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-(11bet; 16alpha-methyl-9alpha-fluoro-1,4-pregnadiene-11beta, 17alpha, 21-triol-2,20-dione; 16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta, 17-alpha, 21-triol-3,2;16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta, 17-alpha, 21-triol-3,20-dione; 16-alpha-methyl-9-alpha-fluoro-11-beta, 17-alpha, 21-trihydroxypregna-1,4-dien; 16alpha-Methyl-9alpha-fluoro-11beta-17alpha-21-trihydroxypregna-1,4-diene-3,20-dione; 16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol
CAS: 50-02-2
MF: C22H29FO5
MW: 392.46
EINECS: 200-003-9
Product Categories: Active Pharmaceutical Ingredients; Antitumors for Research and Experimental Use; Biochemistry; Hydroxyketosteroids; Steroids; Intermediates & Fine Chemicals; Pharmaceuticals; Isotope Labeled Compounds; Steroid and Hormone; Pharmaceutical intermediate; API; MAXIDEX; Hormone Drugs; Mainly used for anti-inflammatory and allergy
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mp 262-264 °C(lit. )
alpha 75 o (c=1, dioxane)
refractive index 76 ° (C=1, Dioxane)
storage temp. 2-8°C
solubility ethanol: 1 mg/mL
form powder
color off-white
Water Solubility 10 mg/100 mL (25 oC)
Merck 14,2943
BRN 2066651
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
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Chemical Properties White Crystalline Solid
Usage A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase
Usage Dexamethasone is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthas .
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Product name | Dexamethasone |
Other name | 16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,2 |
CAS register number | 50-02-2 |
EINECS | 200-003-9 |
Molecular formula | C22H29FO5 |
Molecular weight | 392.46 |
Molecular structure | |
Melting point | 262-264°C |
Assay | 99% |
Product features | Dexamethasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. Dexamethasone is also used to treat certain types of cancer. ? Dexamethasone comes as a tablet and a solution to take by mouth. Your doctor will prescribe a dosing schedule that is best for you. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dexamethasone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. ? Do not stop taking dexamethasone without talking to your doctor. Stopping the drug abruptly can cause loss of appetite, upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. If you take large doses for a long time, your doctor probably will decrease your dose gradually to allow your body to adjust before stopping the drug completely. Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets or oral liquid, even if you switch to an inhalation corticosteroid medication. If these problems occur, call your doctor immediately. You may need to increase your dose of tablets or liquid temporarily or start taking them again. |
Customs clearance | Don& acute;t have to worry about customs pass rate,our customs clearance is 100% |
Product packing | Discreet package .The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration . |
After-sales service | Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible. |
Security shipping | Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you. |
Delivery time | We have stock, so we can delivery quickly at the very day when receive the payment. |
Condition payment | Western union, money gram, T/T, Bitcoin |
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COA :
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Product name | ? Dexamethasone ? |
Batch No. | 20160720 | Ref.Standard | EP 6.0 |
Manu.Date | 2016-07-21 | Date of Analysis | 2016.07.21 |
Inspect Date | 2016-07-21 | Quantity Released | 100KG |
Expiry Date | 2019-07-20 | Report No. | 20160721056 |
Items | Specifications | Results |
Appearance | White or almost white crystalline powder | Conform |
Identification | IR.UV | Conform |
Residue On Ignition | ≤0.2% | 0.14% |
Specific Rotation | +72°~ +80° | +75.8° |
Loss On Drying | ≤0.5% | 0.16% |
Chromatographic Purity | Single impurity:≤0.1% Total impurities: ≤2.0% | 0.38% Conform 0.90% Conform ? |
Chloroform | ≤60ppm | Undetected |
Assay(basis on drying) | 97.0~102.0% | 99.6% |
Conclusion | Be conform with USP35 Standard. |
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# Glucocorticoid Steroids Applications:
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Dexamethasone , a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. Dexamethasone is also used to treat certain types of cancer.
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Dexamethasone comes as a tablet and a solution to take by mouth. Your doctor will prescribe a dosing schedule that is best for you. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dexamethasone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
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Do not stop taking dexamethasone without talking to your doctor. Stopping the drug abruptly can cause loss of appetite, upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. If you take large doses for a long time, your doctor probably will decrease your dose gradually to allow your body to adjust before stopping the drug completely. Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets or oral liquid, even if you switch to an inhalation corticosteroid medication. If these problems occur, call your doctor immediately. You may need to increase your dose of tablets or liquid temporarily or start taking them again.
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# Pharmaceutical Intermediates
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Dexamethasone CAS:50-02-2
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# Local anesthetics
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Benzocaine CAS:94-09-7
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