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Antirheumatics Piroxicam 20 mg Capsule For Rheumatoid Arthritis Treatment

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Description

Piroxicam Medication Capsules 20MG Antirheumatics 1*10& acute;s / box 10*10& acute;s / box

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PIROXICAM?20?MG?Capsules

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COMPOSITION:

Each ADCO-PIROXICAM 20?mg Capsule contains 20?mg piroxicam.

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PHARMACOLOGICAL?ACTION:

ADCO-PIROXICAM?has analgesic, anti-inflammatory and antipyretic properties, and is used in the treatment of rheumatoid arthritis and other rheumatic disorders. Piroxicam acts as an inhibitor of prostaglandin biosynthesis.
ADCO-PIROXICAM?is completely absorbed after oral administration: peak concentrations in plasma occur within two to four hours. Neither food nor antacids alter the rate or extent of absorption.

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INDICATIONS:

ADCO-PIROXICAM?is indicated for a variety of conditions requiring anti-inflammatory and/or analgesic activity, such as rheumatoid arthritis, osteo-arthritis (arthrosis, degenerative joint disease), ankylosing spondylitis, acute musculoskeletal disorders and acute gout.

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CONTRA-INDICATIONS:

ADCO-PIROXICAM should not be used in those patients who have previously shown a hypersensitivity to the drug and patients who have hepatic dysfunction. ADCO-PIROXICAM should be used with caution in patients with a history of gastro-intestinal haemorrhage, ulcers or aspirin sensitivity.

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WARNINGS:

Use in children:
ADCO-PIROXICAM is not recommended for children.

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INTERACTIONS:
ADCO-PIROXICAM should not be used in patients on coumarin-type anticoagulants.?
ADCO-PIROXICAM increases plasma lithium levels.

PREGNANCY AND LACTATION:
ADCO-PIROXICAM should not be used by patients who are pregnant.?
The safety of ADCO-PIROXICAM use during pregnancy or during lactation has not yet been established. ADCO-PIROXICAM inhibits prostaglandin synthesis and release by an effect on prostaglandin biosynthetase. This effect has been associated with an increased incidence of dystocia and delayed parturition in pregnant animals when drug administration was continued into late pregnancy.

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DOSAGE AND DIRECTIONS FOR USE:?
Rheumatoid arthritis, osteo-arthritis (arthrosis, degenerative joint disease), ankylosing spondylitis:
The usual daily dose for the relief of signs and symptoms of rheumatoid arthritis or osteroarthritis is 20?mg given in single or divided doses.?

Acute musculoskeletal disorders:
Therapy should be initiated with 40?mg daily for the first two days, given in single or divided doses.

Acute Gout:
Therapy should be initiated by a single oral dose of 40?mg followed on the next four to six days by 40?mg given in a single or divided daily dosage.



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SIDE-EFFECTS AND SPECIAL PRECAUTIONS:?
In view of the product’s inherent potential to cause fluid retention, heart failure may be precipitated in some compromised patients.
Gastrointestinal symptoms are the most commonly encountered side-effects. Long-term administration of doses higher than 30?mg daily carries an increased risk of gastrointestinal side-effects.
Peptic ulceration and gastrointestinal bleeding have been reported with ADCO-PIROXICAM. Drug administration should be closely supervised in patients with a history of upper gastro-intestinal disease.

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STORAGE INSTRUCTIONS:
Store below 25°C. Protect from light. Keep out of reach of children.

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