Petroleum & Products
120511-73-1 Natural Anti Estrogen Steroids Arimidex Anastrozole White Crystalline Powder
120511-73-1
Description
120511-73-1 Natural Anti Estrogen Steroids Arimidex Anastrozole White Crystalline Powder
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Anastrozole CAS 120511-73-1 Anastrozole
Anastrozole Product Name: Anastrozole,Arimidex
Anastrozole Alias:?Armotraz,Anastrol,Egistrozol,Anastrozolo
Anastrozole CAS NO. : 120511-73-1
Anastrozole Assay : 98%~102%
Anastrozole Appearance : White crystalline powder
Anastrozole Active life cycle : 46 hours
Anastrozole MF:?C17H19N5
Anastrozole MW:?293.37
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Anastrozole COA:
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Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR | Conform with standard IR |
HPLC | Conform with standard HPLC |
Reactive | Conform |
Solubility | Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0℃ | 82.5～83.2℃ |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%～102.0% | 99.80% |
Storage | Cool and dry |
Conclusion | It complies to USP32 . |
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Anastrozole??Description:
Anastrozole (INN) ( Arimidex ) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites.Anastrozole works by inhibiting the synthesis of estrogen. This medication is used to treat breast cancer in women who have gone through & quot;the change of life& quot; (menopause). Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth.
Anastrozole??Usage:
1. Usage in men
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer. Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen--gynecomastia, emotional lability and water retention. Study data suggest dosages of 0.5 mg to 1 mg a day reduce serum estradiol by approximately 50% in men, which differs in postmenopausal women.
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2. Usage in children
Anastrozole may be used off-label in children with precocious puberty, or children with pubertal gynecomastia. Following the onset of puberty, the epiphyseal plate begins to close due to an increased amount of estrogen production escaping local metabolism and spreading to the circulatory system. It is shown to help slow this process, and increase adult height prediction in adolescent males treated with protein-based peptide hormones for the treatment of growth hormone deficiency.
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Contact information:
Name: Miss ?vivian
skype: viviandeng1225
whatsapp: +8615069093656
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