Pharmaceutical Products
Description
Losartan Potassium:
CAS NO: 124750-99-8
Standard: Enterprise Standard
Package: 25kg/barrel
Molecular Formula: C22H22ClKN6O
Molecular Weight: 461.01
Description:
Application:
Assay: ‰￥98.0%
Description:
Losartan is a specific antagonist of the angiotensin II receptor type AT1; it does not inhibit ACE (kininase II), the enzyme that degrades bradykinin. Removal of angiotensin II negative feed back on renin secretion leads to increased plasma renin activity, during losartan administration. A 2 to 3-fold increase in angiotensin II in plasma comes as a result of increases in plasma renin activity. However, antihypertensive activity and suppression of plasma aldosterone concentration are apparent, indicating effective angiotensin II receptor blockade. After discontinuation of losartan, plasma renin activity and angiotensin levels declined.
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Taizhou Tianrui Pharmaceutical Co.,Ltd
nti-tuberculous, Anti-hypertensive, Anti-hyperlipidemic, Anti-bacterial, and Vitamin derivatives APIs and their intermediates productions.
Address: No.168,Xingtai Street,Jiaojiang Zone, Taizhou City, Zhejiang 318000,
Taizhou City, Zhejiang
China, 318000
Tel: +86-(576)-88201638
Fax: +86-(576)-88603302
