Biochemical
Description
A compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Epothilone B may cause complete cell-cycle arrest.
API, epothilone,Read More
Hubei HONCH Pharmaceutical Co.,Ltd
paclitaxel
Address: Room 704, Block A Sakura Plaza, No.2. Luoshi North Road, Wuchang district, Wuhan, ,
wuhan, Hubei
China, 430070
Tel: 86 27 87659162
Fax: 86 27 87654262
