Pharmaceutical Products
Description
Name: D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Synonyms: L-base; Levoamine; D(-)Threo-1-(4-nitrophenyl)-2-amino-1,3-propanediol; (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol;D-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol; Chloromycin base; chloramphenicolbase; (1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL; D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE; D-threo-(1R,2R)-1-p-Nitrophenyl-2-amino-1,3-propanediol; (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol;
CAS Number: 716-61-0
CBNumber: CB6452870
Molecular Formula: C9H12N2O4
Formula Weight: 212.2
API family: Chloramphenicol
Melting point : 163-165 °C(lit.)
Properties: white or slight yellow amorphous Crystalline powder.
Solubility: Hardly soluble in water and slightly soluble in methanol and ethanol.
Packing: 25kg in plastic bag lined drum.
Storage: Sealed, kept in dark place.
Usage
D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (Chloramphenicol base) is an intermediate for synthesizing Chloramphenicol, a broad spectrum antibiotic agent. Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol. Chloramphenicol base per se does not work as an antibiotic, however, it plays an important role in the synthesis and antibacterial activities of chloramphenicol and other new generation antibiotics, represented by thiamphenicol and its experimental analogues, bromamphenicol and methamphenicol.
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Banff Green Technologies, Inc.
diethyl fluoromalonate, dimethyl fluoromalonate, d-p-methyl sulfone phenyl ethyl serinate, florfenicol, d-(-)-threo-2-amino-1-(4-nitrophenyl)-1,3-propanediol, chloramphenicol
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