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Medicine Raw Material Pregabalin 4-Methylpregabalin Powder Cas 148553-50-8

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Description

Medicine Raw Material Pregabalin 4-Methylpregabalin Powder Cas 148553-50-8
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Uses of Pregabalin:
# Pregabalin, is a new type of GABA receptor agonists, can block the voltage dependence calcium channel to reduce the neurotransmitter release, mainly used for clinical treatment of peripheral neuropathy and auxiliary for the treatment of localized part seizures.
# The effectiveness of pregabalin and its older relative ga against these kind of pain syndromes (which tend to respond poorly to other analgesic drugs) has led to their widespread use including as anticonvulsants, muscle relaxants, anxiolytics and mood stabilisers.
# Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.
# It is also commonly prescribed by doctors for many off-label treatments, such as restless leg syndrome, insomnia, and bipolar disorder. There are, however, concerns regarding the quality of the trials conducted for a number of conditions.

Function:
# # 1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
# The main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
# Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Can also be used to treat pain and anxiety.


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Specifications:
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Item | Standard | Result |
Appearance | White or almost white crystalline powder | White crystalline powder |
Specific rotation | +9.0~ +11.5° | +10.79° |
PH | 6.0~8.0 | 6.77 |
Loss on drying | ≤0.5% | 0.02% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤0.002% | <0.002% |
Assay (on dried basis) | ≥98.5% | 100.8% |
R-pregabalin(HPLC) | ≤0.5% | 0.33% |
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Related substances | S-(+)-mandel ≤0.1% | 0.3% |
Unspecific individual impurity≤0.4% | 0.08% |
Total impurities≤1.0% | 0.10% |
Residual solvents | isopropylketone≤3000ppm
tetrahydrofuran≤720ppm | 585.0ppm
ND |
Conclusion | Comply with the enterprise standard |
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Application:
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Pregabalin, is a new type of GABA receptor agonists, can block the voltage dependence calcium channel to reduce the neurotransmitter release, mainly used for clinical treatment of peripheral neuropathy and auxiliary for the treatment of localized part seizures.
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? ? Packaging & Shipping
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1kg/Aluminum foil bag
1kg/ Aluminium Tin
25kg/Drum
25kg/ Aluminum Drum
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Delivery Time:
Usually within 3 working days after confirming the payment.
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Company& acute;s info:
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