Chemicals Stocks
Description
High Purity Sex Steroid Hormones Powder Fulvestrant Faslodex CAS 129453-61-8
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Quick Detail:
Fulvestrant
Fulvestrant?CAS:129453-61-8
Fulvestrant Synonyms: FASLODEX
Fulvestrant?Chemical Name:(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
Fulvestrant?Molecular Fomular:C32H47F5O3S
Fulvestrant?Molecular Weight:606.77
Fulvestrant?Density:1.201 g/cm3
Fulvestrant?Melting Point:104-106°C
Fulvestrant?Boiling Point:674.8 °C at 760 mmHg
Fulvestrant?Appearance:white powder
Fulvestrant?Usage:Antineoplastic (hormonal)
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Dylan
Email:dylan@ycgmp.com
whats app:+8618826067431
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Description:
Fulvestrant Faslodex is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. It is administered as a once-monthly injection.
Fulvestrant Faslodex is approved to treat breast cancer in postmenopausal women. It is used in patients with estrogen receptor positive breast cancer that has metastasized (spread to other parts of the body) after treatment with other antiestrogens.
Fulvestrant Faslodex is also being studied in the treatment of other types of cancer.
High Purity Sex Steroids Powder Fulvestrant Faslodex CAS 129453-61-8
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Applications:
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells. Fulvestrante stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cell has.
Fulvestrante (Faslodex, AstraZeneca) is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works by down-regulating the estrogen receptor.
Fulvestrante is a selective estrogen receptor down-regulator (SERD). Fulvestrante is indicated for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. The dosing schedule for fulvestrante remains under investigation in an attempt to optimize its effectiveness.
Fulvestrante provided effective second-line therapy in this setting for postmenopausal women who had relapsed or progressed after previous endocrine therapy.
In particular 4 clinical trials in this setting did show similar efficacy to the other hormonal agents (aromatase inhibitors and tamoxifen) with good tolerability profile. Fulvestrante had a lower incidence of joint disorders.
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells. Fulvestrante stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cell has.
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High Purity Sex Steroids Powder Fulvestrant Faslodex CAS 129453-61-8
Specifications:
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Test Item | Specification | Results |
Appearance | A white to off-white crystalline powder | A white crystalline powder |
Identification | The retention time of the major peak in the chromatogram of the assay preparation is same as that of the standard preparation obtained in the assay | Conform |
Any Individual impurity | Not more than 0.10% | 0.18% |
Total impurities | Not more than 1.0% | 0.44% |
Ratio of
isomers | Fulvestran A | 50.0%-60.0% | 51.70% |
Fulvestran B | 40.0%-50.0% | 47.86% |
purity | 99.0% | 99.56% |
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Competitive Advantage:
1. Our Company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
2. Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
3. Professional team special for package and shipment and staring on tracking code 24hours for customs pass. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
4. Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
5. High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FedEx, HKEMS,
UPS, etc.
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Guangzhou Huao Chemical Co.,Ltd
Raw Steroid Powders,Injectable Testosterone Steroids,Trenbolone Steroid
Address: Room 1102 1 Unit 16 building South time NANSHA district,
Guangzhou, Guangdong
China, 510000
Tel: 86-20-28165195
Fax: 86-20-28165195