Pharmaceutical Products
Description
1. Basic Information:
Product Name Fluticasone Propionate
Synonym Flutide,CCI18781,Fluticasone17-Propionate
CAS 80474-14-2
MF C25H31F3O5S
MW 500.57
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
2. Quick View:
Fluticasone Propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein. It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn’s disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis.
3. Pharmacology:
Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen, estrogen, or mineralocorticoid receptor thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (e.g. mast cell, eosinophil, neutrophil, macrophages, and lymphocytes) and mediators (e.g. histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability.
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Shenzhen SMQ Bio-tech Co., Ltd.
Steroid powder,cinnamate acid ,pharmaceutical raw material
Address: #2 New District Road, Minzhi Street, Longhua New District,
Shenzhen, Guangdong
China, 518131
Tel: 0755-88320842
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